Given the importance of responsive desire as well as any initial desire, when addressing the subject of hypoactive desire disorder, the entity of women’s arou- sability becomes extremely important. Psychological, contextual, and biological factors influence the processing of stimuli in the woman’s mind. Psychological factors include those from the past to do with her upbringing particularly any losses, traumas (physical, sexual, emotional), her past interpersonal relation- ship—both sexual and nonsexual, encompassing cultural and religious attitudes especially restrictions (17,31,34 – 36). Contextual factors include any current interpersonal difficulties, partner sexual dysfunction, inadequate stimulation, and unsatisfactory sexual and emotional contexts (37 – 41). Medical conditions, psychiatric conditions, medications, substance abuse may all affect her arousabil- ity also (42 – 45).